Concept information
Preferred term
Platelet Factor 4
Type
-
mesh:Descriptor
Definition
- A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Broader concept
Entry terms
- 37270-94-3
- Antiheparin Factor
- Blood platelet factor 4
- Chemokine CXCL4
- CXCL4 Chemokine
- gamma-Thromboglobulin
- Heparin Neutralizing Protein
- PF4 (Platelet Factor 4)
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
37270-94-3
-
Blood platelet factor 4
-
Chémokine CXCL4
-
Chimiokine CXCL4
-
Chimiokine PF-4
-
Chimiokine PF4
-
Facteur antihéparinique
-
Facteur neutralisant l'héparine
-
Facteur plaquettaire-4
-
gamma-Thromboglobuline
-
PF4 (Platelet Factor 4)
-
Protéine CXCL4
-
Protéine neutralisant l'héparine
-
Thromboglobuline gamma
URI
http://data.loterre.fr/ark:/67375/JVR-G5PB78JZ-G
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