Concept information
...
Intercellular Signaling Peptides and Proteins
Cytokines
Hematopoietic Cell Growth Factors
Colony-Stimulating Factors
Preferred term
Granulocyte-Macrophage Colony-Stimulating Factor
Type
-
mesh:Descriptor
Definition
- An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
Broader concept
Entry terms
- 83869-56-1
- Colony-stimulating factor 2
- Colony-Stimulating Factor, Granulocyte-Macrophage
- CSF-2
- CSF-GM
- GM-CSF
- Histamine-Producing Cell-Stimulating Factor
- TC-GM-CSF
- Tumor-Cell Human GM Colony-Stimulating Factor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
-
83869-56-1
-
Colony-stimulating factor 2
-
Facteur de croissance des colonies granulocytaires et macrophagiques
-
Facteur de croissance des granulocytes et macrophages
-
Facteur de croissance des granulocytes-macrophages
-
Facteur de croissance granulocyto-monocytaire
-
Facteur stimulant la formation de colonies de granulocytes et de macrophages
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Facteur stimulant la formation de colonies de neutrophiles et de macrophages
-
Facteur stimulant les colonies de granulocytes et de macrophages
-
Facteur stimulant les colonies de granulocytes-macrophages
-
GM-CSF
-
GMCSF
URI
http://data.loterre.fr/ark:/67375/JVR-G7Q5TK8K-R
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