Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Preferred term
Nod Signaling Adaptor Proteins
Type
-
mesh:Descriptor
Definition
- Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance. Nod signaling adaptor proteins that contain leucine-rich repeat domains.
Broader concept
Narrower concepts
Entry terms
- Nuclear-Binding Oligomerization Domain Proteins
- Nucleotide Oligomerization Domain Proteins
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéines à domaine d'oligomérisation et de liaison de nucléotides
-
Protéines adaptatrices à domaine NOD
-
Protéines NOD
URI
http://data.loterre.fr/ark:/67375/JVR-GG7NFKDX-L
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