Concept information
Preferred term
Muscimol
Type
-
mesh:Descriptor
Definition
- A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Broader concept
Entry terms
- 2763-96-4
- 3(2H)-Isoxazolone, 5-(aminomethyl)-
- Agarin
- Pantherine
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
2763-96-4
-
3(2H)-Isoxazolone, 5-(aminomethyl)-
-
5-Aminométhyl-isoxazol-3-one
-
5-Aminométhylisoxazol-3-one
-
Agarine
-
Panthérine
URI
http://data.loterre.fr/ark:/67375/JVR-GGRBQZ9D-S
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