Concept information
...
Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
...
Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
Preferred term
Immunoglobulin Idiotypes
Type
-
mesh:Descriptor
Definition
- Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Broader concept
Entry terms
- Idiotypes, Immunoglobulin
- Ig Idiotypes
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
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French
-
Idiotypes d'Ig
-
Idiotypes d'immunoglobuline
-
Idiotypes des Ig
URI
http://data.loterre.fr/ark:/67375/JVR-GH46W973-D
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