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Concept information

Preferred term

Genes, bcl-2  

Type

  • mesh:Descriptor

Definition

  • The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.

Broader concept

Entry terms

  • bcl-2 Genes

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-GKKBH8DH-J

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RDF/XML TURTLE JSON-LD Created 6/13/96, last modified 7/8/08