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Concept information

Preferred term

Focal Adhesions  

Type

  • mesh:Descriptor

Definition

  • An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.

Broader concept

Entry terms

  • Adhesion Plaques
  • Cell-Matrix Adherens Junctions
  • Focal Contacts

In other languages

  • French

  • Adhérence focale
  • Contact focal
  • Jonctions adhérentes cellule-matrice
  • Plaques d'adhérence
  • Point de contact focal

URI

http://data.loterre.fr/ark:/67375/JVR-GN58DT57-D

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