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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Niemann-Pick C1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Virus > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Patched Receptors > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Patched Receptors > Niemann-Pick C1 Protein

Preferred term

Niemann-Pick C1 Protein  

Type

  • mesh:Descriptor

Definition

  • A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE.

Broader concept

Entry terms

  • NPC1 Protein

Allowable Qualifier(s)

In other languages

  • Protéine NPC1

    French

  • Protéine de Niemann-Pick C1
  • Protéine Niemann-Pick C1

URI

http://data.loterre.fr/ark:/67375/JVR-GNQ4JHM7-H

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 2/28/18