Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Cyclin-Dependent Kinase Inhibitor Proteins
Preferred term
Cyclin-Dependent Kinase Inhibitor p16
Type
-
mesh:Descriptor
Definition
- A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.
Broader concept
Entry terms
- Cdk4-Associated Protein p16
- CDKN2A Protein
- CDKN2 Protein
- Cyclin-Dependent Kinase Inhibitor-2A
- INK4A Protein
- MTS1 Protein
- Multiple Tumor Suppressor-1
- p16(INK4A)
- p16INK4A Protein
- p16INK4 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Inhibiteur p16 de kinase dépendante de cycline
-
Inhibiteur-2A de kinase cycline-dépendante
-
Inhibiteur-2A de kinase dépendante de cycline
-
p16(INK4A)
-
Protéine CDKN-2
-
Protéine CDKN-2A
-
Protéine CDKN2
-
Protéine CDKN2A
-
Protéine INK-4A
-
Protéine INK4A
-
Protéine MTS-1
-
Protéine MTS1
-
Protéine p16 associée à CDK4
-
Protéine p16(INK4)
-
Protéine p16(INK4A)
URI
http://data.loterre.fr/ark:/67375/JVR-GQSQKP48-C
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