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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > HMG-Box Domains
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > HMG-Box Domains

Preferred term

HMG-Box Domains  

Type

  • mesh:Descriptor

Definition

  • DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

Broader concept

Related concepts

Entry terms

  • High Mobility Group-Box Domains
  • HMG-1-Box Domain
  • HMG-Box Domain

Allowable Qualifier(s)

In other languages

  • Domaines à boîtes HMG

    French

  • Domaines à boites HMG
  • Domaines HMG 1-box
  • Domaines HMG-1-box
  • Domaines HMG-box
  • Domaines HMG1-box

URI

http://data.loterre.fr/ark:/67375/JVR-GWGLLC9M-F

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RDF/XML TURTLE JSON-LD Created 8/3/01, last modified 5/31/16