Concept information
...
Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
...
Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
...
Ion Channels
Potassium Channels
Potassium Channels, Voltage-Gated
Ether-A-Go-Go Potassium Channels
Preferred term
ERG1 Potassium Channel
Type
-
mesh:Descriptor
Definition
- One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
Broader concept
Entry terms
- Ether-A-Go-Go-Related Potassium Channel 1
- Potassium Voltage-Gated Channel, Subfamily H, Member 2
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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Canal potassique-1 apparenté à éther-à-go-go
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Canal potassium ERG1
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Canal potassium-1 apparenté à éther-à-go-go
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Canaux potassiques ERG1
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Canaux potassiques-1 apparentés à éther-à-go-go
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Canaux potassium ERG1
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Canaux potassium-1 apparentés à éther-à-go-go
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Membre-2 de la sous-famille H des Canaux potassiques dépendants du voltage
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Membre-2 de la sous-famille H des Canaux potassiques voltage-dépendants
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Membre-2 de la sous-famille H des Canaux potassium dépendants du voltage
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Membre-2 de la sous-famille H des Canaux potassium voltage-dépendants
URI
http://data.loterre.fr/ark:/67375/JVR-GXLT4JLH-J
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