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Concept information

Preferred term

Aphasia, Primary Progressive  

Type

  • mesh:Descriptor

Definition

  • A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)

Broader concept

Entry terms

  • Mesulam's Syndrome
  • Mesulam Syndrome

In other languages

  • French

  • Aphasie primaire progressive
  • APP (Aphasie Progressive Primaire)
  • Maladie de Mesulam
  • Syndrome de Mesulam

URI

http://data.loterre.fr/ark:/67375/JVR-H18C71F1-H

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