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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Tumor Necrosis Factor > CD40 Antigens
Biological Factors > Immune Checkpoint Proteins > CD40 Antigens
Amino Acids, Peptides, and Proteins > Proteins > Immune Checkpoint Proteins > CD40 Antigens
... > Biological Factors > Antigens > Antigens, Surface > Antigens, Differentiation > Antigens, Differentiation, B-Lymphocyte > CD40 Antigens
Biological Factors > Biomarkers > Antigens, Differentiation > Antigens, Differentiation, B-Lymphocyte > CD40 Antigens

Preferred term

CD40 Antigens  

Type

  • mesh:Descriptor

Definition

  • Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

Broader concept

Related concepts

Entry terms

  • Antigens, CD40
  • CD40 Antigen
  • CDw40 Antigen
  • TNFRSF5 Receptor
  • Tumor Necrosis Factor Receptor Superfamily, Member 5

Allowable Qualifier(s)

In other languages

  • Antigènes CD40

    French

  • Antigène CD40
  • Antigène CDw40
  • CD40
  • Membre-5 de la famille des récepteurs au TNF
  • Membre-5 de la famille des récepteurs du TNF
  • Membre-5 de la superfamille des récepteurs au facteur de nécrose tumorale
  • Membre-5 de la superfamille des récepteurs au TNF
  • Membre-5 de la superfamille des récepteurs du TNF
  • Membre-5 de la superfamille des TNF récepteurs
  • Récepteur TNFRSF-5
  • Récepteur TNFRSF5

URI

http://data.loterre.fr/ark:/67375/JVR-H4KTKNL4-W

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RDF/XML TURTLE JSON-LD Created 5/26/95, last modified 3/27/20