Concept information
Preferred term
Genes, sis
Type
-
mesh:Descriptor
Definition
- Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
Broader concept
Entry terms
- sis Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène sis
URI
http://data.loterre.fr/ark:/67375/JVR-H6R7MJR3-N
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