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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Mannose-Binding Protein-Associated Serine Proteases
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Mannose-Binding Protein-Associated Serine Proteases
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Complement Activating Enzymes > Complement C3-C5 Convertases > Mannose-Binding Protein-Associated Serine Proteases
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Complement Activating Enzymes > Complement C3-C5 Convertases > Mannose-Binding Protein-Associated Serine Proteases

Preferred term

Mannose-Binding Protein-Associated Serine Proteases  

Type

  • mesh:Descriptor

Definition

  • Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Broader concept

Entry terms

  • Mannan-Binding Lectin Serine Proteases
  • Mannose-Binding Protein-Associated Serine Protease
  • MASP
  • MASP Proteases
  • MASPs
  • MBL-Associated Serine Proteases
  • MBP-Associated Serine Protease

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Mannose-Binding Protein-Associated Serine Proteases

    French

  • Mannan-Binding Lectin Serine Proteases
  • Mannose-Binding Potein-Associated Serine Protease
  • MBL-Associated Serine Proteases
  • MBP-Associated Serine Protease
  • Protéases à sérine associées à la protéine liant le mannose
  • Protéines MASP
  • Sérine-protéases associées à la protéine de liaison du mannose
  • Sérine-protéases associées à la proteine liant le mannose
  • Sérine-protéases associées à la protéine MBL
  • Sérine-protéases associées à la protéine MBP

URI

http://data.loterre.fr/ark:/67375/JVR-H8509RP3-B

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 6/17/20