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Immune System Phenomena > Immunomodulation > Immune Tolerance > Self Tolerance > Central Tolerance
... > Therapeutics > Biological Therapy > Immunomodulation > Immune Tolerance > Self Tolerance > Central Tolerance

Preferred term

Central Tolerance  

Type

  • mesh:Descriptor

Definition

  • The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.

Broader concept

Allowable Qualifier(s)

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URI

http://data.loterre.fr/ark:/67375/JVR-H8NBMBFT-7

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RDF/XML TURTLE JSON-LD Created 6/24/11, last modified 6/16/16