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... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Channels > Chloride Channels > Bestrophins
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Channels > Chloride Channels > Bestrophins
Amino Acids, Peptides, and Proteins > Proteins > Eye Proteins > Bestrophins

Preferred term

Bestrophins  

Type

  • mesh:Descriptor

Definition

  • A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.

Broader concept

Entry terms

  • Bestrophin
  • Bestrophin Family
  • Bestrophin Proteins

Allowable Qualifier(s)

In other languages

  • Bestrophines

    French

  • Famille des bestrophines
  • Protéines bestrophines

URI

http://data.loterre.fr/ark:/67375/JVR-H9TLQ12F-S

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/30/21