Concept information
Preferred term
Guanethidine
Type
-
mesh:Descriptor
Definition
- An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Broader concept
Entry terms
- 14920-15-1 (sulfate (1:2))
- ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
- 55-65-2 (Guanethidine)
- 5UBY8Y002G
- 60-02-6 (sulfate (2:1))
- 645-43-2 (sulfate (1:1))
- 87862-38-2 (sulfate (2:1), 14C-labeled)
- 8AQ60474G9
- Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
- Octadine
- Oktadin
- ZTI6C33Q2Q
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
14920-15-1 (sulfate (1:2))
-
55-65-2 (Guanethidine)
-
5UBY8Y002G
-
60-02-6 (sulfate (2:1))
-
645-43-2 (sulfate (1:1))
-
87862-38-2 (sulfate (2:1), 14C-labeled)
-
8AQ60474G9
-
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
-
ZTI6C33Q2Q
URI
http://data.loterre.fr/ark:/67375/JVR-HC985P3V-V
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