Concept information
Preferred term
Genes, myc
Type
-
mesh:Descriptor
Definition
- Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
Broader concept
Entry terms
- myc Genes
Allowable Qualifier(s)
In other languages
-
French
-
Gène myc
URI
http://data.loterre.fr/ark:/67375/JVR-HD9PT452-N
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