Concept information
Preferred term
Proteasome Endopeptidase Complex
Type
-
mesh:Descriptor
Definition
- A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Broader concept
Entry terms
- 20S Proteasome
- Macropain
- Macroxyproteinase
- Multicatalytic Endopeptidase Complex
- Multicatalytic Proteinase
- Prosome
- Proteasome
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Complexe multicatalytique du protéasome
-
Complexe protéasique multicatalytique
-
Complexe protéinasique multicatalytique
-
Macroxyproteinase
-
Prosome
-
Protéase multicatalytique
-
Protéasome
-
Protéasome 20S
URI
http://data.loterre.fr/ark:/67375/JVR-HF0V0TNC-F
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