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Concept information

Cells > Antigen-Presenting Cells > Dendritic Cells, Follicular
Tissues > Lymphoid Tissue > Lymph Nodes > Germinal Center > Dendritic Cells, Follicular

Preferred term

Dendritic Cells, Follicular  

Type

  • mesh:Descriptor

Definition

  • Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.

Entry terms

  • Dendritic Reticulum Cells, Follicular
  • Follicular Dendritic Cells

In other languages

  • French

  • Cellule dendritique folliculaire
  • Cellule folliculaire dendritique
  • Cellules dendritiques des follicules lymphoïdes
  • Cellules folliculaires dendritiques

URI

http://data.loterre.fr/ark:/67375/JVR-HF44MKKC-R

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