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... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists

Preferred term

Histamine H1 Antagonists  

Type

  • mesh:Descriptor

Definition

  • Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.

Broader concept

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Related concepts

Entry terms

  • Antagonists, Histamine H1
  • Antagonists, Histamine H1 Receptor
  • Antihistaminics, H1
  • Blockaders, Histamine H1 Receptor
  • H1 Receptor Blockaders
  • Histamine H1 Antagonist
  • Histamine H1 Blockers
  • Histamine H1 Receptor Antagonist
  • Histamine H1 Receptor Antagonists
  • Histamine H1 Receptor Blockaders
  • Receptor Blockaders, H1

Allowable Qualifier(s)

In other languages

  • Antihistaminiques des récepteurs H1

    French

  • Antagonistes des récepteurs histaminergiques H1
  • Antagonistes H1
  • Anti-histamines H1
  • Anti-histaminiques H1
  • Antihistamines H1
  • Antihistaminiques H1

URI

http://data.loterre.fr/ark:/67375/JVR-HGD6GZ6P-K

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