Concept information
Preferred term
AlkB Homolog 4, Lysine Demethylase
Type
-
mesh:Descriptor
Definition
- A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.
Broader concept
Entry terms
- Alkylated DNA Repair Protein AlkB Homolog 4
- Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Dioxygénase dépendante de l'alpha-cétoglutarate homologue-4 de AlkB
-
Dioxygénase dépendante de l'oxoglutarate homologue-4 de AlkB
-
Lysine déméthylase homologue-4 de AlkB
URI
http://data.loterre.fr/ark:/67375/JVR-HL6J0P0L-F
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