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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > AAA Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > AAA Domain

Preferred term

AAA Domain  

Type

  • mesh:Descriptor

Definition

  • An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis. Highly conserved amino acid motifs that occur in ATP-binding proteins, especially AAA ATPases. They are characterized by the pattern G-x(4)-GK-[TS]; G, K, T and S are GLYCINE; LYSINE; THREONINE; and SERINE, where x can be any amino acid. This motif binds the beta-phosphate of nucleotides.

Broader concept

Related concepts

Entry terms

  • AAA+ Domain
  • AAA Domains
  • AAA Modules
  • AAA+ Modules

Allowable Qualifier(s)

In other languages

  • Domaine AAA

    French

  • Domaine AAA+
  • Domaines AAA
  • Modules AAA
  • Modules AAA+

URI

http://data.loterre.fr/ark:/67375/JVR-HT1687HX-R

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 2/24/17