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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Endonucleases > Endodeoxyribonucleases > DNA Restriction Enzymes > Deoxyribonucleases, Type I Site-Specific
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Deoxyribonucleases > Endodeoxyribonucleases > DNA Restriction Enzymes > Deoxyribonucleases, Type I Site-Specific
Enzymes and Coenzymes > Enzymes > DNA Restriction-Modification Enzymes > DNA Restriction Enzymes > Deoxyribonucleases, Type I Site-Specific

Preferred term

Deoxyribonucleases, Type I Site-Specific  

Type

  • mesh:Descriptor

Definition

  • Enzyme systems containing three different subunits and requiring ATP, S-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent ATPases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognize specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.3.

Broader concept

Entry terms

  • Deoxyribonucleases, Type I, Site Specific
  • Deoxyribonucleases, Type I, Site-Specific
  • DNA Restriction Enzymes, Type I
  • DNase, Site Specific, Type I
  • DNase, Site-Specific, Type I
  • Restriction Endonucleases, Type I
  • Site-Specific DNase, Type I
  • Type I Restriction Enzymes
  • Type I Site Specific Deoxyribonucleases
  • Type I Site-Specific Deoxyribonucleases
  • Type I Site Specific DNase
  • Type I Site-Specific DNase

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-HT9K36DZ-K

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RDF/XML TURTLE JSON-LD Created 5/17/88, last modified 7/9/03