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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Disks Large Homolog 4 Protein
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Disks Large Homolog 4 Protein
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Phosphate Group Acceptor) > Guanylate Kinases > Disks Large Homolog 4 Protein

Preferred term

Disks Large Homolog 4 Protein  

Type

  • mesh:Descriptor

Definition

  • A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.

Broader concept

Related concepts

Entry terms

  • Discs Large Homolog 4 Protein
  • Postsynaptic Density Protein 95
  • PSD-95 Protein
  • PSD95 Protein
  • SAP-90 Protein
  • SAP90 Protein
  • Synapse-Associated Protein 90

Allowable Qualifier(s)

In other languages

  • Homologue-4 de la protéine Disks Large

    French

  • Homologue-4 de la protéine Discs Large
  • Protéine 90 associée aux synapses
  • Protéine 95 de la densité postsynaptique
  • Protéine PSD-95
  • Protéine PSD95
  • Protéine SAP-90
  • Protéine SAP90

URI

http://data.loterre.fr/ark:/67375/JVR-J1MRT6LV-2

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/29/17