Concept information
Preferred term
Fenclonine
Type
-
mesh:Descriptor
Definition
- A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Broader concept
Entry terms
- 14091-08-8 ((D)-isomer)
- 14173-39-8 ((L)-isomer)
- 1991-78-2 (cpd w/o isomeric designation)
- 23633-07-0 (cpd w/o isomeric designation, HCl)
- 51274-82-9 (HCl)
- 55327-86-1 (HBr)
- 7424-00-2 (Fenclonine)
- DL-3-(4-Chlorophenyl)alanine
- DL-Phenylalanine, 4-chloro-
- Fenclonin
- para-Chlorophenylalanine
- p-Chlorophenylalanine
- R5J7E3L9SP
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
14091-08-8 ((D)-isomer)
-
14173-39-8 ((L)-isomer)
-
1991-78-2 (cpd w/o isomeric designation)
-
23633-07-0 (cpd w/o isomeric designation, HCl)
-
51274-82-9 (HCl)
-
55327-86-1 (HBr)
-
7424-00-2 (Fenclonine)
-
DL-Phenylalanine, 4-chloro-
-
p-Chlorophenylalanine
-
Para-chlorophénylalanine
-
Parachlorophénylalanine
-
R5J7E3L9SP
URI
http://data.loterre.fr/ark:/67375/JVR-J1VDMSZP-4
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