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Concept information

Preferred term

beta-Arrestins  

Type

  • mesh:Descriptor

Definition

  • Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.

Broader concept

Entry terms

  • beta-Arrestin

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-J4XTN5J2-J

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 8/9/16