Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Rectal Diseases > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Digestive System Neoplasms > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Neoplasms > Neoplasms by Site > Digestive System Neoplasms > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Colonic Diseases > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Neoplastic Syndromes, Hereditary > Colorectal Neoplasms, Hereditary Nonpolyposis
Neoplasms > Neoplastic Syndromes, Hereditary > Colorectal Neoplasms, Hereditary Nonpolyposis
Nutritional and Metabolic Diseases > Metabolic Diseases > DNA Repair-Deficiency Disorders > Colorectal Neoplasms, Hereditary Nonpolyposis

Preferred term

Colorectal Neoplasms, Hereditary Nonpolyposis  

Type

  • mesh:Descriptor

Definition

  • A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer. HNPCC with no history of associated cancers.

Broader concept

Narrower concepts

Entry terms

  • Familial Nonpolyposis Colon Cancer
  • Hereditary Nonpolyposis Colorectal Neoplasms

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-J72D4TKD-M

Download this concept:

RDF/XML TURTLE JSON-LD Created 6/24/86, last modified 3/5/21