Concept information
Preferred term
NIMA-Interacting Peptidylprolyl Isomerase
Type
-
mesh:Descriptor
Definition
- A highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1.
Broader concept
Entry terms
- Peptidyl-Prolyl Cis-Trans Isomerase Pin1
- Pin1 Peptidylprolyl Isomerase
- PIN1 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Peptidyl-prolyl cis-trans isomerase Pin1
-
Peptidyl-prolyl cis-trans isomérase Pin1
-
Peptidylprolyl isomérase interagissant avec NIMA
-
Peptidylprolyl isomérase Pin1
-
Protéine PIN1
URI
http://data.loterre.fr/ark:/67375/JVR-J85RFQ6W-S
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