Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
CARD Signaling Adaptor Proteins
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Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
CARD Signaling Adaptor Proteins
...
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
CARD Signaling Adaptor Proteins
...
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
CARD Signaling Adaptor Proteins
...
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Nod Signaling Adaptor Proteins
...
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Nod Signaling Adaptor Proteins
Preferred term
Nod2 Signaling Adaptor Protein
Type
-
mesh:Descriptor
Definition
- A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial PEPTIDOGLYCAN. It signals via an N-terminal capase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. Mutations of the gene encoding the nucleotide oligomerization domain 2 protein have been associated with increased susceptibility to CROHN DISEASE.
Broader concept
Entry terms
- CARD15 Protein
- Caspase Recruitment Domain Protein 15
- Nucleotide Oligomerization Domain 2 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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Protéine adaptatrice à domaine NOD-2
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Protéine adaptatrice à domaine NOD2
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Protéine adaptatrice de signalisation NOD-2
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Protéine CARD-15
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Protéine CARD15
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Protéine NOD-2
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Protéine NOD2
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Protéine-15 à domaine de recrutement des caspases
URI
http://data.loterre.fr/ark:/67375/JVR-J8PGH9W7-H
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