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Concept information

Preferred term

Nod2 Signaling Adaptor Protein  

Type

  • mesh:Descriptor

Definition

  • A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial PEPTIDOGLYCAN. It signals via an N-terminal capase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. Mutations of the gene encoding the nucleotide oligomerization domain 2 protein have been associated with increased susceptibility to CROHN DISEASE.

Entry terms

  • CARD15 Protein
  • Caspase Recruitment Domain Protein 15
  • Nucleotide Oligomerization Domain 2 Protein

In other languages

  • French

  • Protéine adaptatrice à domaine NOD-2
  • Protéine adaptatrice à domaine NOD2
  • Protéine adaptatrice de signalisation NOD-2
  • Protéine CARD-15
  • Protéine CARD15
  • Protéine NOD-2
  • Protéine NOD2
  • Protéine-15 à domaine de recrutement des caspases

URI

http://data.loterre.fr/ark:/67375/JVR-J8PGH9W7-H

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 3/30/16