Concept information
Preferred term
In Situ Nick-End Labeling
Type
-
mesh:Descriptor
Definition
- An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
Broader concept
Entry terms
- In Situ Nick End Labeling
- In Situ Nick End-Labeling
- In Situ Nick End Labelling
- In Situ Nick End-Labelling
- In Situ Nick-End Labelling
- Nick End-Labeling, In Situ
- Nick-End Labeling, In Situ
- Nick End-Labelling, In Situ
- Nick-End Labelling, In Situ
- TUNEL
Allowable Qualifier(s)
In other languages
-
French
-
Marquage in situ d'extrémités de brins d'ADN
-
Technique TUNEL
-
TUNEL (Terminal Uridine Nick-End Labeling)
URI
http://data.loterre.fr/ark:/67375/JVR-J9BZVDQF-B
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