Concept information
Preferred term
Ethacrynic Acid
Type
-
mesh:Descriptor
Definition
- A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Broader concept
Entry terms
- 58-54-8 (Ethacrynic Acid)
- 6500-81-8 (Na salt)
- Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-
- Etacrynic Acid
- Ethacrinic Acid
- K41MYV7MPM
- M5DP350VZV
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
58-54-8 (Ethacrynic Acid)
-
6500-81-8 (Na salt)
-
Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-
-
K41MYV7MPM
-
M5DP350VZV
URI
http://data.loterre.fr/ark:/67375/JVR-J9RLT5D9-6
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