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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Colony-Stimulating Factor > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Colony-Stimulating Factor > Proto-Oncogene Proteins c-kit

Preferred term

Proto-Oncogene Proteins c-kit  

Type

  • mesh:Descriptor

Definition

  • A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

Broader concept

Related concepts

Entry terms

  • Antigens, CD117
  • CD117 Antigen
  • CD117 Antigens
  • c-kit Protein
  • c-kit Receptor
  • kit Proto-Oncogene Protein
  • p145 c-kit
  • p145(c-kit)
  • p145c-kit
  • Proto-Oncogene Protein c-kit
  • Proto-Oncogene Protein kit
  • Receptor, Stem Cell Factor
  • SCF Receptor
  • Stem Cell Factor Receptor

Allowable Qualifier(s)

In other languages

  • Protéines proto-oncogènes c-kit

    French

  • Antigène CD117
  • CD117
  • p145(c-kit)
  • Protéine c-kit
  • Protéine du proto-oncogène kit
  • Protéine p145(c-kit)
  • Protéine proto-oncogène c-kit
  • Protéine proto-oncogène kit
  • Récepteur au facteur de croissance des cellules souches
  • Récepteur au facteur des cellules souches
  • Récepteur au SCF
  • Récepteur c-kit
  • Récepteur du facteur de croissance des cellules souches
  • Récepteur du facteur des cellules souches
  • Récepteur du SCF

URI

http://data.loterre.fr/ark:/67375/JVR-JK7GX4D2-1

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RDF/XML TURTLE JSON-LD Created 5/26/95, last modified 5/21/21