Concept information
...
Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Receptor Tyrosine Kinase-like Orphan Receptors
Type
-
mesh:Descriptor
Definition
- A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.
Broader concept
Entry terms
- Neurotrophic Tyrosine Kinase, Receptor-related Proteins
- NTRKR Receptors
- Receptor Tyrosine Kinase-like Orphan Receptor
- ROR Tyrosine Kinase Receptors
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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Protéines de type récepteur à tyrosine kinase neurotrophique
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Protéines de type récepteur tyrosine-kinase neurotrophique
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Récepteurs à tyrosine kinase ROR
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Récepteurs orphelins apparentés aux récepteurs à tyrosine kinase
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Récepteurs orphelins de type récepteur tyrosine-kinase
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Récepteurs orphelins de type RTK
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Récepteurs tyrosine-kinases ROR
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ROR (Receptor tyrosine kinase-like Orphan Receptor)
URI
http://data.loterre.fr/ark:/67375/JVR-JLQ96KL5-2
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