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Biological Factors > Toxins, Biological > Mycotoxins > Aflatoxins > Aflatoxin B1
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Benzopyrans > Aflatoxins > Aflatoxin B1
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrans > Benzopyrans > Aflatoxins > Aflatoxin B1

Preferred term

Aflatoxin B1  

Type

  • mesh:Descriptor

Definition

  • A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.

Broader concept

Entry terms

  • 10279-73-9 (cis(+-)-isomer)
  • 1162-65-8 (Aflatoxin B1)
  • 43043-21-6 (14C-labeled cpd(6aR-cis)-isomer)
  • 77076-87-0 (2H-labeled cpd(6aR-cis)-isomer)
  • 77076-88-1 (3H-labeled cpd(6aR-cis)-isomer)
  • 84415-24-7 (di-HCl(6aR-cis)-isomer)
  • 9N2N2Y55MH
  • Aflatoxin B(1)
  • Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Aflatoxine B1

    French

  • 10279-73-9 (cis(+-)-isomer)
  • 1162-65-8 (Aflatoxin B1)
  • 43043-21-6 (14C-labeled cpd(6aR-cis)-isomer)
  • 77076-87-0 (2H-labeled cpd(6aR-cis)-isomer)
  • 77076-88-1 (3H-labeled cpd(6aR-cis)-isomer)
  • 84415-24-7 (di-HCl(6aR-cis)-isomer)
  • 9N2N2Y55MH
  • Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-

URI

http://data.loterre.fr/ark:/67375/JVR-JNV7N2ZL-P

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RDF/XML TURTLE JSON-LD Created 1/24/91, last modified 5/27/20