Concept information
...
Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
...
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Proto-Oncogene Proteins c-met
Type
-
mesh:Descriptor
Definition
- Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.
Entry terms
- c-met Proteins
- c-Met Receptor Tyrosine Kinase
- Hepatocyte Growth Factor Receptor
- HGF Receptor
- met Proto-Oncogene Proteins
- MET Proto-Oncogene, Receptor Tyrosine Kinase
- MET Receptor Tyrosine Kinase
- Receptor, Hepatocyte Growth Factor
- Receptor, HGF
- Receptor, Scatter Factor
- Scatter Factor Receptor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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Protéines c-met
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Protéines du proto-oncogène met
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Récepteur à l'HGF
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Récepteur au facteur de croissance des hépatocytes
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Récepteur au facteur de croissance hépatocytaire
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Récepteur au facteur de dispersion
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Récepteur de l'HGF
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Récepteur du facteur de croissance des hépatocytes
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Récepteur du facteur de croissance hépatocytaire
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Récepteur du facteur de dispersion
URI
http://data.loterre.fr/ark:/67375/JVR-JNZHSZXD-9
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