Concept information
Preferred term
Cytochrome P-450 CYP1A1
Type
-
mesh:Descriptor
Definition
- A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Broader concept
Entry terms
- 7-Ethoxyresorufin O-Deethylase
- CYP 1A1
- CYP1A1
- CYP1A1 Protein
- Cytochrome P450 IA1
- EROD
- Ethoxyresorufin Dealkylase
- Ethoxyresorufin O-Deethylase
- Ethylresorufin O-Deethylase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
CYP 1A1
-
CYP1A1
-
Cytochrome P450 1A1
-
EROD
-
Éthoxyrésorufine-O-dééthylase
URI
http://data.loterre.fr/ark:/67375/JVR-JPNSL7G2-B
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