Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Preferred term
Ataxia Telangiectasia Mutated Proteins
Type
-
mesh:Descriptor
Definition
- A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
Broader concept
Entry terms
- ATM Protein
- AT Mutated Protein
- A-T Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéine ATM
-
Protéines mutées dans l'ataxie-télangiectasies
-
Protéines mutées dans le syndrome d'ataxie-télangiectasie
-
Protéines mutées dans le syndrome de Louis-Bar
URI
http://data.loterre.fr/ark:/67375/JVR-JR2W1QZL-0
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