Concept information
Preferred term
Serotonin Plasma Membrane Transport Proteins
Type
-
mesh:Descriptor
Definition
- Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS. A sodium chloride-dependent neurotransmitter symporter located on the PLASMA MEMBRANE of BLOOD PLATELETS. It transports SEROTONIN from the EXTRACELLULAR SPACE into the platelet CYTOPLASM.
Broader concept
Entry terms
- 5-Hydroxytryptamine Plasma Membrane Transport Protein
- Neurotransmitter Transporters, Serotonin-Specific
- Neurotransmitter Transport Proteins, Serotonin-Specific
- Serotonin Plasma Membrane Transporter Proteins
- Serotonin Transporter
- SERT Proteins
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéines de transport de la sérotonine
-
Protéines SERT
-
Transporteur de la 5HT
-
Transporteur de la sérotonine
-
Transporteurs membranaires de la sérotonine
URI
http://data.loterre.fr/ark:/67375/JVR-JV96S544-Z
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