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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on CH-NH Group Donors > Oxidoreductases, N-Demethylating > Cytochrome P-450 CYP3A
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 3 > Cytochrome P-450 CYP3A
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 3 > Cytochrome P-450 CYP3A
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 3 > Cytochrome P-450 CYP3A

Preferred term

Cytochrome P-450 CYP3A  

Type

  • mesh:Descriptor

Definition

  • A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. A specific subtype of CYP3A. A specific subtype of CYP3A.

Broader concept

Entry terms

  • CYP3A
  • Cytochrome P450 3A
  • Cytochrome P-450IIIA
  • Erythromycin N-Demethylase

Allowable Qualifier(s)

In other languages

  • Cytochrome P-450 CYP3A

    French

  • CYP 3A
  • CYP3A
  • Cytochrome P-450IIIA
  • Cytochrome P450 3A
  • Erythromycin N-demethylase
  • Érythromycine N-déméthylase

URI

http://data.loterre.fr/ark:/67375/JVR-JXDQ5PR7-S

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 5/27/16