Concept information
Preferred term
Phenobarbital
Type
-
mesh:Descriptor
Definition
- A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Broader concept
Narrower concepts
Entry terms
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-
- 50-06-6 (Phenobarbital)
- 57-30-7 (mono-Na salt)
- Phenemal
- Phenobarbitone
- Phenylbarbital
- Phenylethylbarbituric Acid
- SW9M9BB5K3
- YQE403BP4D
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-
-
50-06-6 (Phenobarbital)
-
57-30-7 (mono-Na salt)
-
SW9M9BB5K3
-
YQE403BP4D
URI
http://data.loterre.fr/ark:/67375/JVR-K1W2MB1W-6
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