Concept information
...
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
STAT Transcription Factors
Preferred term
STAT5 Transcription Factor
Type
-
mesh:Descriptor
Definition
- A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
Broader concept
Entry terms
- Signal Transducer and Activator of Transcription 5
- STAT5 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Facteur de transcription STAT5
-
Facteur transcriptionnel STAT-5
-
Facteur transcriptionnel STAT5
-
Facteur-5 transducteur du signal et activateur de la transcription
-
Protéine STAT-5
-
Protéine STAT5
URI
http://data.loterre.fr/ark:/67375/JVR-K36BZM19-Z
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