Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class II
Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class II
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Histocompatibility Antigens Class II
Biological Factors > Antigens > Antigens, Surface > Histocompatibility Antigens > Histocompatibility Antigens Class II
Biological Factors > Antigens > Isoantigens > Histocompatibility Antigens > Histocompatibility Antigens Class II

Preferred term

Histocompatibility Antigens Class II  

Type

  • mesh:Descriptor

Definition

  • Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Antigens, Immune Response
  • Class II Antigen
  • Class II Antigens
  • Class II Histocompatibility Antigen
  • Class II Histocompatibility Antigens
  • Class II Major Histocompatibility Antigen
  • Class II Major Histocompatibility Antigens
  • Class II Major Histocompatibility Molecules
  • Class II MHC Proteins
  • I-A Antigen
  • I-A-Antigen
  • IA Antigen
  • Ia Antigens
  • Ia-Like Antigen
  • Ia-Like Antigens
  • Immune Response Antigens
  • Immune-Response-Associated Antigens
  • MHC Class II Molecule
  • MHC Class II Molecules
  • MHC-II Molecules
  • MHC II Peptide
  • MHC II Peptides

Allowable Qualifier(s)

In other languages

  • Antigènes d'histocompatibilité de classe II

    French

  • Antigène d'histocompatibilité de classe II
  • Antigène de classe II
  • Antigène I-A
  • Antigène IA
  • Antigènes associés à la réponse immune
  • Antigènes d'histocompatibilité de classe 2
  • Antigènes d'histocompatibilité majeurs de classe II
  • Antigènes de classe II
  • Antigènes de classe II du complexe majeur d'histocompatibilité
  • Antigènes de la réponse immune
  • Antigènes du CMH de classe II
  • Antigènes majeurs d'histocompatibilité de classe II

URI

http://data.loterre.fr/ark:/67375/JVR-K6ZGJCK5-W

Download this concept:

RDF/XML TURTLE JSON-LD Created 5/13/80, last modified 6/30/21