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Concept information

Preferred term

G-Quadruplexes  

Type

  • mesh:Descriptor

Definition

  • Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)

Entry terms

  • Guanine-Quadruplexes

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-K8LBS2W2-G

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