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Concept information

Preferred term

Leukemia, Large Granular Lymphocytic  

Type

  • mesh:Descriptor

Definition

  • A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.

Broader concept

Entry terms

  • Aggressive Natural Killer Cell Leukemia
  • Aggressive NK Cell Leukemia
  • Large Granular Lymphocyte Leukemia
  • Leukemia, LGL
  • Leukemia, Lymphocytic, Large Granular
  • LGL Leukemia
  • Lymphoproliferative Disease of Granular Lymphocytes
  • Lymphoproliferative Disease of Large Granular Lymphocytes

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-KCQ7W7SV-V

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