Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27

Preferred term

Cyclin-Dependent Kinase Inhibitor p27  

Type

  • mesh:Descriptor

Definition

  • A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.

Broader concept

Entry terms

  • 147604-94-2
  • CDK Inhibitor p27
  • CDKN1B Protein
  • CDKN4 Protein
  • Cyclin-Dependent Kinase Inhibitor 1B
  • p27 CDK Inhibitor
  • p27 Kip1 Protein
  • p27Kip1 Protein

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Inhibiteur p27 de kinase cycline-dépendante

    French

  • 147604-94-2
  • Inhibiteur p27 de CDK
  • Inhibiteur p27 de kinase dépendante de cycline
  • Inhibiteur-1B de kinase cycline-dépendante
  • Inhibiteur-1B de kinase dépendante de cycline
  • Protéine CDKN-1B
  • Protéine CDKN-4
  • Protéine CDKN1B
  • Protéine CDKN4
  • Protéine p27(Kip1)

URI

http://data.loterre.fr/ark:/67375/JVR-KH15TK52-L

Download this concept:

RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 11/23/15