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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Contractile Proteins > Muscle Proteins > Troponin > Troponin I
Macromolecular Substances > Multiprotein Complexes > Troponin > Troponin I
... > Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microfilament Proteins > Troponin > Troponin I
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Troponin > Troponin I
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Troponin > Troponin I
... > Macromolecular Substances > Polymers > Biopolymers > Microfilament Proteins > Troponin > Troponin I

Preferred term

Troponin I  

Type

  • mesh:Descriptor

Definition

  • A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Broader concept

Entry terms

  • Troponin-I

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-KKSPB8VG-Z

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RDF/XML TURTLE JSON-LD Created 6/10/96, last modified 7/6/16