Concept information
Preferred term
Glomerulonephritis, Membranoproliferative
Type
-
mesh:Descriptor
Definition
- Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. A type of mesangiocapillary glomerulonephritis that is characterized by immune deposits on the endothelial side of the GLOMERULAR BASEMENT MEMBRANE leading to splitting and reduplication of the basement membrane. A type of mesangiocapillary glomerulonephritis that is characterized by the dark bands of electron-dense deposits in the GLOMERULAR BASEMENT MEMBRANE caused by autoantibodies against ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb). A type of mesangiocapillary glomerulonephritis that is characterized by subepithelial immune deposit and may be a variant of type I.
Broader concept
Entry terms
- Glomerulonephritis, Hypocomplementemic
- Glomerulonephritis, Mesangiocapillary
- Membranoproliferative Glomerulonephritis
- Mesangiocapillary Glomerulonephritis
- MPGN
Allowable Qualifier(s)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemically induced (Qualifier)
- classification (Qualifier)
- complications (Qualifier)
- congenital (Qualifier)
- diagnosis (Qualifier)
- diagnostic imaging (Qualifier)
- diet therapy (Qualifier)
- drug therapy (Qualifier)
- economics (Qualifier)
- embryology (Qualifier)
- enzymology (Qualifier)
- epidemiology (Qualifier)
- ethnology (Qualifier)
- etiology (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- mortality (Qualifier)
- nursing (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiopathology (Qualifier)
- prevention & control (Qualifier)
- psychology (Qualifier)
- radiotherapy (Qualifier)
- rehabilitation (Qualifier)
- surgery (Qualifier)
- therapy (Qualifier)
- urine (Qualifier)
- veterinary (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Glomérulonéphrite membrano-proliférative
-
Glomérulonéphrite mésangio-capillaire
-
Glomérulonéphrite mésangiocapillaire
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GNMP
-
GNMP (GloméruloNéphrite MLembrano-Proliférative)
URI
http://data.loterre.fr/ark:/67375/JVR-KNF49J4P-Z
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