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... > Diagnosis > Diagnostic Techniques and Procedures > Clinical Laboratory Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed
Investigative Techniques > Clinical Laboratory Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed
Investigative Techniques > Immunologic Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed

Preferred term

Lymphocyte Culture Test, Mixed  

Type

  • mesh:Descriptor

Definition

  • Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.

Broader concept

Entry terms

  • Leukocyte Culture Test, Mixed
  • Mixed Leukocyte Culture Test
  • Mixed Leukocyte Reaction
  • Mixed Lymphocyte Culture Test
  • Mixed Lymphocyte Reaction

Allowable Qualifier(s)

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URI

http://data.loterre.fr/ark:/67375/JVR-KP60WBVF-L

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